| Description |
viii, 401 p. : ill. ; 24 cm. |
| Series |
Drugs and the pharmaceutical sciences ; 84
|
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Pt.1. Bioavailability of pharmaceutical enzymes -- Biopharmaceuticl aspects of enzyme absorption -- The endothelium monolayer: barrier to enzyme and drug delivery -- Pt.2. Tailoring of pharmaceutical enzymes -- Enzyme- albumin conjugates: advantages and problems with targeting -- Acyl enzymes as prodrugs -- Molecular modeling of pharmaceutically important targets -- Pt.3. Biochemical and pharmacological properties -- The cysteine proteinases from the latex of Carica papaya L -- Bromelain -- Hyaluronidase -- Pancreatic enzyme replacement -- I- asparaginase: an essential antineoplastic drug -- Macrophage-targeted glucocerebrosidase: a therapeutically effective enzyme replacement product for Gaucher Disease -- Deoxyribonuclease I -- Therapeutic protein inhibitors of elastase -- Pt.4. Standardization and methodology -- Good standardization practices -- Assays. |
| Subject |
Enzymes -- Therapeutic use
|
|
Enzymes -- Testing
|
| Added Author |
Lauwers, Albert
|
|
Scharpé, Simon 1944-
|
| ISBN |
0824793757 (alk. paper) |
|
