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LEADER 00000nam a2200265 a 4500 
001    u21027 
001    21513 
003    SIRSI 
005    20060625233800.0 
008    030606s1997    xxu00000000000001100eng0d 
020    0824793757 (alk. paper) 
049    JURF 
050 00 RM666.E55|bP476 1997 
245 00 Pharmaceutical enzymes /|cedited by Albert Lauwers, Simon 
       Scharpé. 
260    New York :|bMarcel Dekker,|c1997 
300    viii, 401 p. :|bill. ;|c24 cm. 
440  0 Drugs and the pharmaceutical sciences ;|v84 
504    Includes bibliographical references and index. 
505 0  Pt.1. Bioavailability of pharmaceutical enzymes -- 
       Biopharmaceuticl aspects of enzyme absorption -- The 
       endothelium monolayer: barrier to enzyme and drug delivery
       -- Pt.2. Tailoring of pharmaceutical enzymes -- Enzyme- 
       albumin conjugates: advantages and problems with targeting
       -- Acyl enzymes as prodrugs -- Molecular modeling of 
       pharmaceutically important targets -- Pt.3. Biochemical 
       and pharmacological properties -- The cysteine proteinases
       from the latex of Carica papaya L -- Bromelain -- 
       Hyaluronidase -- Pancreatic enzyme replacement -- I- 
       asparaginase: an essential antineoplastic drug -- 
       Macrophage-targeted glucocerebrosidase: a therapeutically 
       effective enzyme replacement product for Gaucher Disease -
       - Deoxyribonuclease I -- Therapeutic protein inhibitors of
       elastase -- Pt.4. Standardization and methodology -- Good 
       standardization practices -- Assays. 
650  0 Enzymes|xTherapeutic use 
650  0 Enzymes|xTesting 
700 1  Lauwers, Albert 
700 1  Scharpé, Simon|d1944-