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LEADER 00000cam a2200277 a 4500 
001    u4037 
001    3542 
003    SIRSI 
005    20020930144900.0 
008    991110s2000    xxua     b    001 0 eng   
020    089603531X (alk. paper) 
050 00 RM301.63|bD785 2000 
245 00 Drug targeting :|bstrategies, principles, and applications
       /|cedited by G.E. Francis and Cristina Delgado. 
260    Totowa, N.J. :|bHumana Press,|c2000. 
263    0004 
300    x, 318 p. :|bill. ;|c24 cm. 
440  0 Methods in molecular medicine ;|v25 
504    Includes bibliographical references and index. 
505 0  Pt.1. Strategies -- Chemical construction of immunotoxins 
       -- Construction of ribonuclease-antibody conjugates for 
       selective cytotoxicity -- Intracellular targeting using 
       bispecific antibodies -- Antibody conjugation methods for 
       active targeting of liposomes -- Folate as a targeting 
       device for proteins utilizing folate receptor-mediated 
       endocytosis -- Preparation of recombinant RNase single-
       chain antibody fusion proteins -- Pt.2. Theoretical 
       aspects -- Practical considerations in the exploitation of
       passive tumor targeting -- Effect of dose, molecular size,
       and binding affinity on uptake of antibodies -- Inhibition
       of tumor blood flow -- Pt.3. Applications -- Targeting in 
       myocardial infarction -- Targeting HIV-infected cells -- 
       Making fusion toxins to targetleukemia and lymphoma -- 
       Antibody-bearing liposomes as chloroquine vehicles in 
       treatment of murine malaria -- Immunotargeting of catalase
       to the pulmonary vascular endothelium -- Targeted gene 
       transfer: a practical guide based on experience with lipid
       -based plasmid delivery systems 
650  0 Drug delivery systems 
650  0 Drug carriers (Pharmacy) 
700 1  Francis, G. E 
700 1  Delgado, Cristina